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C-ESTA® Serum

Lift, firm and tighten the appearance of facial contours with this exceptional antioxidant cocktail featuring Vitamin C & DMAE for powerful free-radical protection.

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C-ESTA® Serum
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C-ESTA Serum and Marini Physical Protectant were used in a recent study.

Published in the Journal of Drugs and Dermatology (JDD). Split-Face Vitamin C Consumer Preference Study, Leslie Baumann, MD, Deysi K. Duque, MS, Michael J. Schirripa, PhD. 2014; 13(10): 1208-1213

A favorite of Meghan Markle

Whether Meghan Markle is getting ready for her royal wedding, or on the television set of "Suits", Jan Marini Skin Research products are one of her favorite go-to solutions.

AOL.com: Read More | US Weekly: Read More | Insider: Read More| Allure: Read More


Great for all skin types, C-ESTA Serum is a powerful antioxidant cocktail, featuring Vitamin C and DMAE, shown to reduce the appearance of fine lines and wrinkles and uneven skin texture. Preferred by subjects in a blinded split-face study vs. a leading Vitamin C solution, C-ESTA Serum is the preferred Vitamin C and antioxidant solution for younger, healthier looking skin.

1 oz. pump
8 oz. bottle for Clinical/Professional use only

Key Ingredients

  • Ascorbyl Palmitate (Vitamin C)
  • DMAE
  • Hyaluronic Acid
  • Vitamins (B5 & E)

Skin Types


Usage Instructions

Shake bottle well. Apply sparingly morning and evening to clean skin. Apply over entire face, neck and behind ears.


Water/Aqua/Eau, Ascorbyl Palmitate, Urea, Butylene Glycol Dicaprylate/Dicaprate, Dimethicone, Acetyl Tyrosine, Dimethyl MEA, Fragrance (Parfum), Zinc Sulfate, Sodium Hydroxide, Tocopheryl Acetate, Panthenol, Sodium Hyaluronate, Ergothioneine, Pyridoxine HCl, Sodium Metabisulfite, Sodium Sulfite, Xanthan Gum, Disodium EDTA, Citric Acid, Farnesol, Linalool, Amyl Cinnamal, Benzyl Salicylate, Cinnamal, Limonene, Eugenol, Gerianol, Hydroxycitronellal, Butylphenyl Methylpropional, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol


"We love the C-ESTA Serum from JMSR and see it as one of the most comprehensively recommended products for our patient base. From those that are in the early 20's through our Baby Boomer patients and beyond, C-ESTA is commonly recommended with rave reviews from users and is consistently one of our top sellers in this line, and among Vitamin C products. Jan Marini has many extraordinary products with C-ESTA Serum clearly being included in that category."

Joel Schlessinger MD, FAAD, FAACS
Board Certified Dermatologist and Cosmetic Surgeon
Omaha, NE

One of our best sellers, C-ESTA Serum, continues to produce fabulous results for our clients that are looking for a good Vitamin C product. Bright, smooth and tighter looking skin keeps clients coming back for this effective product. I recommend this product to my facial surgery patients to help prolong the results of their surgery.

Lee D. Robinson, M.D., P.C.
Lake Oswego, OR

"Our patients tell us that this product is a "face lift in a bottle." It really complements any facial treatment or laser service that we offer. The skin's appearance is measurably firmer and tighter. The appearance of wrinkles is dramatically reduced. C-ESTA remains one of our best selling JMSR products."

Nanette Broderick
Plastic Surgery Offices of Dr. Daryl Hoffman & Dr. Kirk Churukian
Los Gatos, CA

"I have been using the C-ESTA product line by Jan Marini Skin Research for nearly 12 years on patients, staff members and myself. This dynamic antioxidant solution has integrated well into both our rejuvenation and maintenance skin care regimes. User compliance with C-ESTA protocols has been exceptional, and we have noted that these patients are very satisfied with the clinical benefits of using this product."

Carlos Puig, MD
Katy, TX

"Jan Marini C-ESTA Serum is my favorite topical Vitamin C. It combines other essential factors to improve the appearance of fine lines and skin firmness. It is very easy to apply and feels great on the skin. With daily application, skin looks more youthful within a short period of time."

Noushin Parastouk, MD
Irvine, CA

"I truly love Jan Marini's C-ESTA Serum! It is hands-down one of my favorite JMSR products. The light sweet smell, creamy texture and overall improvement I see in my skin, make it by far the best Vitamin C product on the market! I use C-ESTA Serum daily on my face, neck and chest, and can't imagine this not being part of my daily skin care regime!"

Ashley Forsberg, Clinical Esthetician
Offices of Gary McCracken, MD
Scottsdale, AZ