Clinical Study Summaries

Age Intervention® Retinol Plus MD

STUDY DESIGN

  • 33 subjects between 20-75 years old with moderate photo-aging
  • AM/PM usage of the SCMS and Retinol Plus MD following a 3 week acclimation period

CONCLUSION

  • 100% of subjects noted improvement in skin smoothness, luminosity, texture and pore size at 12 weeks
  • 94% of subjects noted improvement in skin elasticity and the appearance of fine lines and wrinkles at 12 weeks
  • 94% of subjects noticed skin improvement by week 6
  • 94% of subjects would purchase and recommend the product
  • 100% of subjects rated Retinol Plus MD moderately to significantly superior to previously used retinol products (n=15)
  • 100% of subjects rated Retinol Plus MD equal or superior to prescription retinoids (n=13)

Authors: Jacqueline Calkin, MD; Kelly Bomer, MD; and Sanjay Grover, MD

Regeneration Booster

STUDY DESIGN

  • 20 subjects between 35-75 years old with moderate degree of photo-aging (Glogau wrinkle scale score ll-lll)
  • Subjects were instructed to use only Regeneration Booster, a gentle cleanser and sunscreen

CONCLUSION

  • 100% of subjects noted improvement in overall skin quality
  • 100% of subjects noted improvement in at least 3 or more categories with an average improvement in 6.7 of 8 categories including: wrinkles, texture, pore size, elasticity, skin color/clarity, erythema, hydration and overall skin quality
  • 100% of subjects noted positive user experience
  • Significant improvement in 100% of measured categories
  • 0 cases of sensitivity, acclimation or irritation

Author: Robert Weiss, MD

Age Intervention® Enlighten MD

STUDY DESIGN

  • 20 female subjects between 30-65 years old with hyperpigmentation on the face secondary to photo-aging and melasma
  • AM/PM usage of the SCMS and Enlighten MD following a 3 week acclimation period

CONCLUSION

  • 75% of subjects with melasma (9 of 12) experienced a reduction in MASI scores
  • 74% of subjects experienced a reduction in photo-aging
  • 100% of subjects reported improvement in their skin in at least 2 or more categories
  • 95% of subjects indicated improved skin quality
  • 89% subjects indicated a positive intent to purchase (17 of 19)
  • High subject satisfaction with no reported cases of irritation or acclimation problems
  • 95% study subject completion rate

Author: Jacqueline Calkin, MD

Age Intervention® Duality MD™

STUDY DESIGN

  • 21 subjects (19 female and 2 male) between the ages of 20-29 with mild to moderate acne
  • AM/PM usage of the SCMS and Duality MD following a 3 week acclimation period

CONCLUSION

  • 100% of subjects experienced a reduction in acne lesion counts
  • Improvement was statistically significant by week 4 and continued to improve through study completion
  • 64% average lesion count reduction (range 36% to 78%)
  • 100% of subjects experienced significant improvement in skin quality by blinded photographic review
  • Significant improvement in both skin quality and acne by subject and physician assessment
  • High subject satisfaction with no reported cases of irritation or excessive drying

Author: Jaggi Rao, MD

Age Intervention® Dark Circle Eye Defense

STUDY DESIGN

  • 20 female subjects between 30-65 years old
  • Subjects were instructed to use Dark Circle Eye Defense once-nightly

CONCLUSION

  • 100% of subjects noted improvement in the appearance of discoloration and wrinkles in self-assessment
  • Dermatologist assessment noted significant improvement in the appearance of dark circles in 100% of subjects by day 45
  • Quantified measurement noted statistically significant improvement in subjects by day 15

Authors: Fulvio Marzatico, Ph.D.; Michela Quaglini, Ph.D.; and Angela Michelotti, Ph.D.

Skin Care Management System™

STUDY DESIGN

  • 32 female subjects between 23-62 years old assigned into one or more of the following categories: Acne, Hyperpigmentation, Rosacea, Overall Skin Rejuvenation
  • Subjects were instructed to use the SCMS as directed morning and evening

CONCLUSION

  • 100% of subjects showed visible photographic improvements
  • 100% reported that they would continue to use and purchase the SCMS
  • 87% of subjects’ immediate family and peers noted visible improvements
  • 31 of 32 subjects observed no acclimation period

Author: Jan Marini Skin Research, Inc.